منابع مشابه
RSC_mb_C005144F 1821..1828
Intrinsic disorder is believed to contribute to the ability of some proteins to interact with multiple partners which is important for protein functional promiscuity and regulation of the cross-talk between pathways. To better understand the mechanisms of molecular recognition through disordered regions, here, we systematically investigate the coupling between disorder and binding within domain...
متن کاملJohn Langdon Down (1828 – 1896)
When John Down was 18 years old, he had some kind of mystical experience. He met a girl that appeared so peculiar, that he felt sorry for her and, consciously or unconsciously, would spend his whole life searching for this phenomenon. He decided to study Medicine, became the director of the largest “Asylum for Idiots” in England and wrote articles and books about the thing that fascinated him s...
متن کاملOp-molb130082 1816..1829
The Piwi-interacting RNA (piRNA) pathway defends animal genomes against the harmful consequences of transposable element (TE) infection by imposing small-RNA-mediated silencing. Because silencing is targeted by TE-derived piRNAs, piRNA production is posited to be central to the evolution of genome defense. We harnessed genomic data sets from Drosophila melanogaster, including genome-wide measur...
متن کاملOp-brai130113 1816..1829
After stroke, penumbral salvage determines clinical recovery. However, the rescued penumbra may be affected by selective neuronal loss, as documented both histopathologically in animals and using the validated in vivo positron emission tomography marker C-flumazenil in humans. However, whether the non-infarcted penumbra is capable of neuronal activation, and how selective neuronal loss may inte...
متن کاملAndrew Taylor Still, 1828–1917
there is a statistically-based portrait, but the author's findings are largely negative. The group was older (a natural consequence of their training and careers before politics) and initially they were more likely to identify with political parties of the left, until the whole character of the legislature itself shifted in that direction by the end of the century. But for the most part, the ph...
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ژورنال
عنوان ژورنال: وقائع تاریخیة
سال: 2020
ISSN: 2682-471X
DOI: 10.21608/hev.2020.115490